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1

In vitro and in vivo siRNA delivery to hepatocyte utilizing ternary complexation of lactosylated dendrimer/cyclodextrin conjugates, siRNA and low-molecular-weight sacran

Hayashi, Yuya, Higashi, Taishi, Motoyama, Keiichi, Jono, Hirofumi, Ando, Yukio, Arima, Hidetoshi

Journal:

International Journal of Biological Macromolecules

Year:

2017

Language:

english

File:

PDF, 829 KB

english, 2017

2

The pharmacology of the integrins

Dermot Cox, Toshiaki Aoki, Jiro Seki, Yukio Motoyama, Keizo Yoshida

Journal:

Medicinal Research Reviews

Year:

1994

Language:

english

File:

PDF, 1.92 MB

english, 1994

3

Electrochemical processing of Cu and Ni nanowire arrays

Munekazu Motoyama, Yasuhiro Fukunaka, Tetsuo Sakka, Yukio H. Ogata, Shiomi Kikuchi

Journal:

Journal of Electroanalytical Chemistry

Year:

2005

Language:

english

File:

PDF, 491 KB

english, 2005

4

Design, synthesis, and evaluation of fibrinogen inhibitors, ω-(p-amidinophenoxy) alkanoylaspartic acid derivatives

Akito Tanaka, Hiroyoshi Sakai, Takatoshi Ishikawa, Isao Nakanishi, Mitsuru Ohkubo, Toshiaki Aoki, Yukio Motoyama, Hisashi Takasugi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 366 KB

english, 1996

5

Design, synthesis, and evaluation of orally active fibrinogen inhibitors

Akito Tanaka, Hiroyoshi Sakai, Takatoshi Ishikawa, Toshiaki Aoki, Yukio Motoyama, Hisashi Takasugi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 372 KB

english, 1997

6

synthesis and biological activity of 4-methyl-3,5-dioxane derivatives as thromboxane a2 receptor antagonists

Hiroshi Marusawa, Hiroyuki Setoi, Akio Kuroda, Akihiko Sawada, Jiro Seki, Yukio Motoyama, Hirokazu Tanaka

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 265 KB

english, 1999

7

Prediction of the no-reflow phenomenon during percutaneous coronary intervention using coronary computed tomography angiography

Hiroto Harigaya, Sadako Motoyama, Masayoshi Sarai, Kaori Inoue, Tomonori Hara, Masanori Okumura, Hiroyuki Naruse, Junnichi Ishii, Hitoshi Hishida, Yukio Ozaki

Journal:

Heart and Vessels

Year:

2011

Language:

english

File:

PDF, 291 KB

english, 2011

8

IgA nephropathy associated with leukemia and lymphoma: report of two cases

Osamu Motoyama, Yasuko Kojima, Akira Ohara, Ichirou Tsukimoto, Yukio Ishikawa, Kikuo Iitaka

Journal:

Clinical and Experimental Nephrology

Year:

2008

Language:

english

File:

PDF, 348 KB

english, 2008

9

123I-BMIPP and99mTc-TF discordance on myocardial scintigraphy and it’s correlation with functional recovery following acute myocardial infarction: role of conventional echocardiography

Shankar K. Biswas, Masayoshi Sarai, Hiroshi Toyama, Akira Yamada, Sadako Motoyama, Hiroto Harigaya, Tomonori Hara, Masatsugu Iwase, Hitoshi Hishida, Yukio Ozaki

Journal:

The International Journal of Cardiovascular Imaging

Year:

2009

Language:

english

File:

PDF, 300 KB

english, 2009

10

The washout rate of123I-BMIPP and the evolution of left ventricular function in patients with successfully reperfused ST-segment elevation myocardial infarction: comparisons with the echocardiography

Shankar K. Biswas, Masayoshi Sarai, Akira Yamada, Hiroshi Toyama, Sadako Motoyama, Hiroto Harigaya, Tomonori Hara, Hiroyuki Naruse, Hitoshi Hishida, Yukio Ozaki

Journal:

The International Journal of Cardiovascular Imaging

Year:

2010

Language:

english

File:

PDF, 315 KB

english, 2010

11

In vitro gene delivery mediated by lactosylated dendrimer (generation 3, G3)/α-cyclodextrin conjugates into hepatocytes

Keiichi Motoyama, Yoshimasa Mori, Shogo Yamashita, Yuya Hayashi, Hirofumi Jono, Yukio Ando, Fumitoshi Hirayama, Kaneto Uekama, Hidetoshi Arima

Journal:

Journal of Inclusion Phenomena and Macrocyclic Chemistry

Year:

2011

Language:

english

File:

PDF, 344 KB

english, 2011

12

Evaluation of plaque instability

Sadako Motoyama, Yukio Ozaki, Jagat Narula

Journal:

Current Cardiovascular Imaging Reports

Year:

2009

Language:

english

File:

PDF, 644 KB

english, 2009

13

Synthesis and Biological Activity of 1-Phenylsulfonyl-4-Phenylsulfonylaminopyrrolidine Derivatives as Thromboxane A2 Receptor Antagonists

Hiroshi Marusawa, Hiroyuki Setoi, Akihiko Sawada, Akio Kuroda, Jiro Seki, Yukio Motoyama, Hirokazu Tanaka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 299 KB

english, 2002

14

REG I enhances chemo- and radiosensitivity in squamous cell esophageal cancer cells

Kaori Hayashi, Satoru Motoyama, Souichi Koyota, Yukio Koizumi, Jingshu Wang, Shin Takasawa, Asako Itaya-Hironaka, Sumiyo Sakuramoto-Tsuchida, Kiyotomi Maruyama, Hajime Saito, Yoshihiro Minamiya, Jun-i

Journal:

Year:

2008

Language:

english

File:

PDF, 187 KB

english, 2008

15

FK633: A Potent and Selective Platelet GPIIb/IIIa Antagonist

Toshiaki Aoki, Kayoko Harada, Jiro Seki, Akito Tanaka, Hisashi Takasugi, Yukio Motoyama

Journal:

Cardiovascular Therapeutics

Year:

1999

Language:

english

File:

PDF, 91 KB

english, 1999

16

TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

Naka, Kazuhito, Hoshii, Takayuki, Muraguchi, Teruyuki, Tadokoro, Yuko, Ooshio, Takako, Kondo, Yukio, Nakao, Shinji, Motoyama, Noboru, Hirao, Atsushi

Journal:

Year:

2010

Language:

english

File:

PDF, 626 KB

english, 2010

17

REG Iα is a Reliable Marker of Chemoradiosensitivity in Squamous Cell Esophageal Cancer Patients

Kaori Hayashi, Satoru Motoyama, Toshihiro Sugiyama, Jun-ichi Izumi, Akira Anbai, Hiroshi Nanjo, Hitoshi Watanabe, Kiyotomi Maruyama, Yoshihiro Minamiya, Souichi Koyota, Yukio Koizumi, Shin Takasawa, K

Journal:

Annals of Surgical Oncology

Year:

2008

Language:

english

File:

PDF, 282 KB

english, 2008

18

In Vitro and In Vivo gene delivery mediated by Lactosylated Dendrimer/α-Cyclodextrin Conjugates (G2) into Hepatocytes

Hidetoshi Arima, Shogo Yamashita, Yoshimasa Mori, Yuya Hayashi, Keiichi Motoyama, Kenjiro Hattori, Tomoko Takeuchi, Hirofumi Jono, Yukio Ando, Fumitoshi Hirayama, Kaneto Uekama

Journal:

Journal of Controlled Release

Year:

2010

Language:

english

File:

PDF, 764 KB

english, 2010

19

The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models

Takehiro Ochi, Yukio Motoyama, Toshio Goto

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 234 KB

english, 2000

20

Possible inhibitory mechanism of FK506 (tacrolimus hydrate) ointment for atopic dermatitis based on animal models

Takanori Sengoku, Kyoko Morita, Shozo Sakuma, Yukio Motoyama, Toshio Goto

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 356 KB

english, 1999

21

Antinociceptive properties of FR140423 mediated through spinal δ-, but not μ- and κ-, opioid receptors

Takehiro Ochi, Takashi Fujii, Yukio Motoyama, Toshio Goto

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 121 KB

english, 1999

22

In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist

Yasuko Kato, Yasuhiro Kita, Mie Nishio, Yoshimi Hirasawa, Kiyotaka Ito, Toshio Yamanaka, Yukio Motoyama, Jiro Seki

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 124 KB

english, 1999

23

A new prostaglandin E1 analogue (TFC-612) prevents a decrease in motor nerve conduction velocity in streptozocin-diabetic rats

Hitoshi Yasuda, Masanobu Sonobe, Ikuo Hatanaka, Makio Yamashita, Yasufumi Miyamoto, Masahiko Terada, Masanori Amenomori, Ryuichi Kikkawa, Yukio Shigeta, Yukio Motoyama, Noriyuki Saito

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 387 KB

english, 1988

24

The anti-platelet actions of FR122047, a novel cyclooxygenase inhibitor

Miwako Dohi, Yoshihiko Sakata, Jiro Seki, Yasuko Namikawa, Jiro Fujisaki, Akito Tanaka, Hisashi Takasugi, Yukio Motoyama, Keizo Yoshida

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 483 KB

english, 1993

25

Electrochemical metal deposition on silicon

Yukio H. Ogata, Katsutoshi Kobayashi, Munekazu Motoyama

Journal:

Current Opinion in Solid State & Materials Science

Year:

2006

Language:

english

File:

PDF, 538 KB

english, 2006

26

Fatty acid metabolism and myocardial perfusion imaging for the evaluation of global left ventricular dysfunction following acute myocardial infarction: Comparisons with echocardiography

Shankar Kumar Biswas, Masayoshi Sarai, Akira Yamada, Sadako Motoyama, Hiroto Harigaya, Tomonori Hara, Kunihiko Sugimoto, Hiroshi Toyama, Hitoshi Hishida, Yukio Ozaki

Journal:

International Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 667 KB

english, 2010

27

The spinal antinociceptive effect of FR140423 is mediated through kyotorphin receptors

Takehiro Ochi, Yukio Motoyama, Toshio Goto

Journal:

Year:

2000

Language:

english

File:

PDF, 551 KB

english, 2000

28

Comparison of the Antithrombotic Effects of FK633, GPIIb/IIIa Antagonist, and Aspirin in a Guinea Pig Thrombosis Model

Toshiaki Aoki, Dermot Cox, Kayoko Senzaki, Jiro Seki, Akito Tanaka, Hisashi Takasugi, Yukio Motoyama

Journal:

Thrombosis Research

Year:

1998

Language:

english

File:

PDF, 172 KB

english, 1998

29

7.5L: Late-News Paper: Developments of a 145-inch Diagonal Super Hi-Vision Plasma Display Panel

Keiji Ishii, Takenobu Usui, Yukio Murakami, Yasushi Motoyama, Masahiko Seki, Yasuyuki Noguchi, Takashi Furutani, Tomoki Nakakita, Takeru Yamashita

Journal:

SID Symposium Digest of Technical Papers

Year:

2012

Language:

english

File:

PDF, 356 KB

english, 2012

30

Effect of TFC-612, a 7-thia prostaglandin El derivative, on intimal thickening after endothelial injury with balloon catheter in rats

Yukio Motoyama, Jiro Seki, Yasuko Katoh, Mie Nishio, Keizo Yoshida

Journal:

Atherosclerosis

Year:

1994

Language:

english

File:

PDF, 661 KB

english, 1994

31

FK409, a new nitric-oxide donor, suppresses smooth muscle proliferation in the rat model of balloon angioplasty

Jiro Seki, Mie Nishio, Yasuko Kato, Yukio Motoyama, Keizo Yoshida

Journal:

Atherosclerosis

Year:

1995

Language:

english

File:

PDF, 1.44 MB

english, 1995

32

IMPACT OF CORONARY ATHEROSCLEROSIS IN JAPANESE WOMEN WITH CHRONIC KIDNEY DISEASE

Hideki Kawai, Masayoshi Sarai, Hiroto Harigaya, Hajime Ito, Sadako Motoyama, Yukio Ozaki

Journal:

Journal of the American College of Cardiology

Year:

2011

Language:

english

File:

PDF, 242 KB

english, 2011

33

The effects of TFC-612, a 7-thia prostaglandin E1 derivative, on platelet function

Yukio Motoyama, Yoshihiko Sakata, Jiro Seki, Takashi Asada, Yasuko Namikawa, Haruo Horiai, Takaharu Ono

Journal:

Thrombosis Research

Year:

1991

Language:

english

File:

PDF, 629 KB

english, 1991

34

The effects of TFC-612, a 7-thia prostaglandin E1 derivative, on platelet function

Yukio Motoyama, Yoshihiko Sakata, Jiro Seki, Takashi Asada, Yasuko Namikawa, Haruo Horiai, Takaharu Ono

Journal:

Thrombosis Research

Year:

1991

Language:

english

File:

PDF, 645 KB

english, 1991

35

TFC-612, a prostaglandin E1 derivative, enhances fibrinolytic activity in rats

Yukio Motoyama, Yoshihiko Sakata, Jiro Seki, Miho Sato, Yasuko Namikawa, Haruo Horiai, Takaharu Ono

Journal:

Thrombosis Research

Year:

1992

Language:

english

File:

PDF, 592 KB

english, 1992

36

Urinary Concentration of Neutrophil Gelatinase-associated Lipocalin and Risk of Acute Kidney Injury in Patients Hospitalized for Worsening Heart Failure

Ryunosuke Okuyama, Junichi Ishii, Kousuke Hattori, Tousei Hashimoto, Hiroyuki Naruse, Sadako Motoyama, Shigeru Matsui, Hideo Izawa, Yukio Ozaki

Journal:

Journal of Cardiac Failure

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

37

Prognostic Value of Plasma Concentration of D-dimer on Admission for In-hospital Mortality in Patients Hospitalized for Worsening Heart Failure

Tousei Hashimoto, Junichi Ishii, Ryunosuke Okuyama, Hiroyuki Naruse, Yoshihisa Mori, Shigeru Matsui, Sadako Motoyama, Hideo Izawa, Yukio Ozaki

Journal:

Journal of Cardiac Failure

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

38

Multislice Computed Tomographic Characteristics of Coronary Lesions in Acute Coronary Syndromes

Sadako Motoyama, Takeshi Kondo, Masayoshi Sarai, Atsushi Sugiura, Hiroto Harigaya, Takahisa Sato, Kaori Inoue, Masanori Okumura, Junichi Ishii, Hirofumi Anno, Renu Virmani, Yukio Ozaki, Hitoshi Hishid

Journal:

Journal of the American College of Cardiology

Year:

2007

Language:

english

File:

PDF, 1.35 MB

english, 2007

39

Noninvasive Coronary Angiography With a Prototype 256-Row Area Detector Computed Tomography System Comparison With Conventional Invasive Coronary Angiography

Sadako Motoyama, Hirofumi Anno, Masayoshi Sarai, Takahisa Sato, Yoshihiro Sanda, Yukio Ozaki, Teruhito Mochizuki, Kazuhiro Katada, Hitoshi Hishida

Journal:

Journal of the American College of Cardiology

Year:

2008

Language:

english

File:

PDF, 504 KB

english, 2008

40

Computed Tomographic Angiography Characteristics of Atherosclerotic Plaques Subsequently Resulting in Acute Coronary Syndrome

Sadako Motoyama, Masayoshi Sarai, Hiroto Harigaya, Hirofumi Anno, Kaori Inoue, Tomonori Hara, Hiroyuki Naruse, Junichi Ishii, Hitoshi Hishida, Nathan D. Wong, Renu Virmani, Takeshi Kondo, Yukio Ozaki,

Journal:

Journal of the American College of Cardiology

Year:

2009

Language:

english

File:

PDF, 745 KB

english, 2009

41

Reply

Sadako Motoyama, Yukio Ozaki, Jagat Narula

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 109 KB

english, 2010

42

Serial Coronary CT Angiography–Verified Changes in Plaque Characteristics as an End Point: Evaluation of Effect of Statin Intervention

Kaori Inoue, Sadako Motoyama, Masayoshi Sarai, Takahisa Sato, Hiroto Harigaya, Tomonori Hara, Yoshihiro Sanda, Hirofumi Anno, Takeshi Kondo, Nathan D. Wong, Jagat Narula, Yukio Ozaki

Journal:

Journal of the American College of Cardiology: Cardiovascular Imaging

Year:

2010

Language:

english

File:

PDF, 831 KB

english, 2010

43

P-116 Impact of Defect Score and Washout Rate of 123I-BMIPP on Left Ventricular Functional Recovery Following Acute Myocardial Infarction

Shankar Kumar Biswas, Masayoshi Sarai, Hiroshi Toyama, Akira Yamada, Sadako Motoyama, Hiroto Harigaya, Tomonori Hara, Hiroyuki Naruse, Hitoshi Hishida, Yukio Ozaki

Journal:

CVD Prevention and Control

Year:

2009

Language:

english

File:

PDF, 53 KB

english, 2009

44

Design and evaluation of polyamidoamine dendrimer conjugate with PEG, α -cyclodextrin and lactose as a novel hepatocyte-selective gene carrier in vitro and in viv o

Hayashi, Yuya, Higashi, Taishi, Motoyama, Keiichi, Mori, Yoshimasa, Jono, Hirofumi, Ando, Yukio, Arima, Hidetoshi

Journal:

Journal of Drug Targeting

Year:

2013

Language:

english

File:

PDF, 595 KB

english, 2013

45

Dilated coronary arterial obstruction due to coronary artery microfistulae

Kawai, Hideki, Motoyama, Sadako, Sarai, Masayoshi, Ozaki, Yukio

Journal:

Journal of Cardiovascular Computed Tomography

Year:

2013

Language:

english

File:

PDF, 1014 KB

english, 2013

46

Coil migration into coronary sinus: A rare complication of percutaneous transhepatic obliteration of portal systemic collaterals

Kawai, Hideki, Kato, Yasuchika, Motoyama, Sadako, Sarai, Masayoshi, Ozaki, Yukio

Journal:

Journal of Cardiovascular Computed Tomography

Year:

2013

Language:

english

File:

PDF, 654 KB

english, 2013

47

Systemic delivery of transthyretin siRNA mediated by lactosylated dendrimer/α-cyclodextrin conjugates into hepatocyte for familial amyloidotic polyneuropathy therapy

Hayashi, Yuya, Mori, Yoshimasa, Higashi, Taishi, Motoyama, Keiichi, Jono, Hirofumi, Sah, Dinah W. Y., Ando, Yukio, Arima, Hidetoshi

Journal:

Year:

2012

Language:

english

File:

PDF, 807 KB

english, 2012

48

Antiplatelet Agents Based on Cyclooxygenase Inhibition without Ulcerogenesis. Evaluation and Synthesis of 4,5-Bis(4-methoxyphenyl)-2-substituted-thiazoles

Tanaka, Akito, Sakai, Hiroyoshi, Motoyama, Yukio, Ishikawa, Takatoshi, Takasugi, Hisashi

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.39 MB

english, 1994

49

Impact of Accompanying Hydrogen Generation on Metal Nanotube Electrodeposition

Motoyama, Munekazu, Fukunaka, Yasuhiro, Ogata, Yukio H., Prinz, Friedrich B.

Journal:

Journal of The Electrochemical Society

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

50

Potential Use of Lactosylated Dendrimer (G3)/α-Cyclodextrin Conjugates as Hepatocyte-Specific siRNA Carriers for the Treatment of Familial Amyloidotic Polyneuropathy

Hayashi, Yuya, Mori, Yoshimasa, Yamashita, Shogo, Motoyama, Keiichi, Higashi, Taishi, Jono, Hirofumi, Ando, Yukio, Arima, Hidetoshi

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 2.65 MB

english, 2012

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